| MolecularFormula: | C24H25ClFN5O3 |
| MolecularWeight: | 589.71g/mol |
| CASNumber: | 220127-57-1 |
| Appearance: | Whitetoslightlyyellowpowder |
| Solubility: | SolubleinDMSOandwater.Sparinglysolubleinmethanol |
| Purity: | ≥99% |
| Storage: | -20ºC |
MaterialSafetyDataSheet
Date:Oct21,2015
1.PRODUCTANDCOMPANYIDENTIFICATION
1.1Productidentifier
Productname:ImatinibMesylate
CatalogNo:1100175002,1100170013,1100170023,1100170053,1100170103
1.2Relevantidentifiedusesofthesubstanceormixtureandusesadvisedagainst
Forresearchuseonly.
1.3Detailsofthesupplierofthesafetydatasheet
Company:EtonBioscienceInc
TollFree:1-800-758-1630
Tel:1-800-758-1630
Fax:1-800-507-2912
1.4Emergencytelephonenumber
1-800-758-1630
2.HAZARDSIDENTIFICATION
2.1Classificationofthesubstanceormixture
Acutetoxicity:oral,Category4
2.2GHSLabelelements,includingprecautionarystatements
Pictogram
SignalWord | Warning |
HazardStatement | |
H302 | Harmfulifswallowed |
Precautionarystatement | |
P264 | Washskinthoroughlyafterhandling |
P302+P312 | IFSWALLOED:CallaPOISONCENTERordoctor/physicianifyoufeelunwell. |
P330 | Rinsemouth |
P501 | Disposeofcontents/containertoanapprovedwastedisposalplant |
2.3Otherhazards
None
3.COMPOSITION/INFORMATIONONINGREDIENTS
3.1Substances
4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-phenyl]benzamidemethanesulfonate
MolecularFormula:C₂₉H₃₁N₇O.CH₄SO₃
MolecularWeight:589.71g/mol
CASNo:220127-57-1
4.FIRSTAIDMEASURES
4.1Descriptionoffirstaidmeasures
Eyecontact
Checkforandremovecontactlensesandflushwithcopiousamountsofwater;assureadequateflushingbyseparatingtheeyelidswithfingers;callaphysician
SkinContact
flushwithcopiousamountsofwater;removecontaminatedclothingandshoes;callaphysician
Inhalation
Ifinhaled,removetofreshair;ifbreathingisdifficult,giveoxygen;ifbreathingstops,giveartificialrespiration
Ingestion
ifswallowed,washoutmouthwithcopiousamountsofwater;callaphysician
4.2Mostimportantsymptomsandeffects,bothacuteanddelayed
Noinformationavailable
4.3Indicationofanyimmediatemedicalattentionandspecialtreatmentneeded.
Noinformationavailable
5.FIREFIGHTINGMEASURES
5.1Extinguishingmedia
Suitableextinguishingmedia
waterspray,carbondioxide,drychemicalpowderorfoam
5.2Specialhazardsarisingfromthesubstanceormixture
Noinformationavailable
5.3Adviceforfirefighters
Wearself-containedbreathingapparatusandprotectiveclothingtopreventcontactwithskinandeyes.
6.ACCIDENTALRELEASEMEASURES
6.1Personalprecautions,protectiveequipmentandemergencyprocedures
Usefullpersonalprotectiveequipment.Evacuatepersonneltosafeareas.
6.2Environmentalprecautions
Preventfurtherleakageorspillage.Preventproductfromenteringdrain.
6.3Methodsandmaterialforcontainmentandcleaningup
Absorbsolutionswithfinely-powderedliquid-bindingmaterial(diatomite,universalbinders);decontaminatesurfacesandequipmentbyscrubbingwithalcohol;disposeofcontaminatedmaterialaccordingtoSection13
7.HANDLINGANDSTORAGE
7.1Precautionsforsafehandling
Avoidskin/eyecontact.Useprotectiveequipmentasneeded.Washcontaminatedclothingbeforereuse.
7.2Conditionsforsafestorage,includinganyincompatibilities
Keepcontainertightlyclosedinacool,well-ventedplace.Storeat-20˚C.
7.3Specificenduse(s)
Nodataavailable.
8.EXPOSURECONTROLS/PERSONALINFORMATION
8.1ControlParameters
Thisproductcontainsnohazardousmaterialswithoccupationalexposurelimits.
8.2Exposurecontrols
Engineeringcontrols
Provideshowerandeyewashstation
Personalprotectiveequipment
EyeProtection | Wearsafetygoggles |
SkinProtection | Wearprotectiveclothing |
HandProtection | Wearprotectivegloves |
Respiratoryprotection | WearNIOSH/MSHAapprovedrespirators |
9.PHYSICALANDCHEMICALPROPERTIES
9.1Informationonbasicphysicalandchemicalproperties
Appearance | Solid |
pH | Nodataavailable |
Meltingpoint | Nodataavailable |
Freezingpoint | Nodataavailable |
Boilingpoint | Nodataavailable |
Density | Nodataavailable |
Watersolubility | Verypoorlysoluble |
9.2Othersafetyinformation
Nodataavailable.
10.STABILITYANDREACTIVITY
10.1Reactivity
Nodataavailable
10.2Chemicalstability
Stableunderrecommendedstorageconditions.
10.3Possibilityofhazardousreactions
Nodataavailable.
10.4Conditionstoavoid
Protectfromlightandheat
10.5IncompatIBLematerials
strongoxidizingagents
10.6Hazardousdecompositionproducts
Thermaldecompositionmayproducetoxicgasessuchascarbonmonoxide,carbondioxide,andnitrogenoxides
11.TOXICOLOGICALINFORMATION
11.1Informationontoxicologicaleffects
Toxicologicaleffectsonthisproducthavenotbeenthoroughlystudied.
12.ECOLOGICALINFORMATION
12.1Toxicity
Avoidreleaseintoenvironment
12.2Persistenceanddegradability
Nodataavailable
12.3.Bioaccumulativepotential
Nodataavailable
12.4Mobilityinsoil
Nodataavailable
12.5ResultsofPBTandvPvBassessment
Nodataavailable
12.6Otheradverseeffects
Nodataavailable
13.DISPOSALINFORMATION
13.1Wastetreatmentmethods
Disposeinaccordancewithlocal,state,andfederalregulations.
14.TRANSPORTINFORMATION
DOT:
Propershippingname:none
Non-Hazardousfortransport:thissubstanceisconsideredtobenon-hazardousfortransport
IATA:
Propershippingname:none
Non-Hazardousfortransport:thissubstanceisconsideredtobenon-hazardousfortransport
IMDG:
Propershippingname:none
Non-Hazardousfortransport:thissubstanceisconsideredtobenon-hazardousfortransport
15.REGULATORYINFORMATION
EURiskandSafetyphrases:
R22:Harmfulifswallowed
S22:Donotbreathedust
S24/25:Avoidcontactwithskinandeyes
S26:Incaseofcontactwitheyes,rinseimmediatelywithplentyofwaterandseekmedicaladvice
S28:aftercontactwithskin,washimmediatelywithplentyofwater
S36/37/39:Wearsuitableprotectiveclothing,glovesandeye/faceprotection
16.OTHERINFORMATION
Everest Biotech公司成立于2000年，由英国牛津大学一批生物化学家创建。公司科学家团队具有丰富的抗体纯化及蛋白组学专业知识，雄厚的专业背景赋予了公司能为全球科研人员提供高质量、创新性抗体产品的能力。目前，Everest Biotech可提供3000余种抗体，涉及肿瘤、自身免疫、过敏、心血管疾病、传染病、代谢、神经科学等领域。所有抗体均由Everest Biotech自主研发生产、全部经过肽亲和纯化以保证最佳的特异性和纯度、经过免疫原肽的ELISA和WB实验验证; 由PhD科学家团队提供全方位技术支持服务。Everest Biotech为众多国际知名抗体公司提供OEM服务。
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